eGFR Calculator
Estimate glomerular filtration rate in adults using the race-free 2021 CKD-EPI creatinine equation.
Input & Computation
The 2021 CKD-EPI creatinine equation is race-free. It uses sex-specific creatinine constants but does not include a race coefficient. eGFR is reported in mL/min/1.73 m\u00b2 and is intended for adults aged 18 and older.
Enter Patient Values
All calculations run locally in your browser. No data is transmitted or stored.
Enter the patient’s age.
Sex used by the equation
Enter a serum creatinine value.
Conversion: 1 mg/dL = 88.4 µmol/L.
Interpretation Guide
2021 CKD-EPI Equation
eGFR = 142 \u00d7 min(Scr/\u03ba,1)^\u03b1 \u00d7 max(Scr/\u03ba,1)^\u22121.200 \u00d7 0.9938^Age \u00d7 (1.012 if female)
GFR Categories (mL/min/1.73 m\u00b2)
- G1 (90–Infinity) \u2014 Normal or high
- G2 (60–89) \u2014 Mildly decreased
- G3a (45–59) \u2014 Mildly to moderately decreased
- G3b (30–44) \u2014 Moderately to severely decreased
- G4 (15–29) \u2014 Severely decreased
- G5 (<15) \u2014 Kidney failure range
Evidence & References
Inker LA et al. (2021)
New creatinine- and cystatin C-based equations to estimate GFR without race. New England Journal of Medicine 385(20):1737–1749. Source of the race-free 2021 CKD-EPI creatinine equation.
National Kidney Foundation
CKD-EPI Creatinine Equation (2021). Clinical practice guidance for estimating glomerular filtration rate in adults.
eGFR = 142 \u00d7 min(Scr/\u03ba,1)^\u03b1 \u00d7 max(Scr/\u03ba,1)^\u22121.200 \u00d7 0.9938^Age \u00d7 (1.012 if female). Female: \u03ba=0.7, \u03b1=\u22120.241. Male: \u03ba=0.9, \u03b1=\u22120.302. Race coefficient: not used. Result in mL/min/1.73 m\u00b2.
PM Lab Suite
Clinical Laboratory Intelligence Platform
When to Use
- Estimating GFR in adults aged 18 years and older
- CKD staging and monitoring when serum creatinine is available
- Drug dosing decisions requiring a GFR estimate (per product-specific guidance)
- Outpatient renal function assessment with standardized creatinine assays
Common Pitfalls
- Not intended for patients under 18 years
- Unreliable in rapidly changing kidney function or acute kidney injury
- Less accurate with unusual muscle mass, amputation, severe malnutrition, or pregnancy
- A single eGFR does not establish CKD — chronicity and other markers are required
- Race coefficient is intentionally not used in the 2021 equation