PM PregaMind

EV-OMICS Laboratory

Extracellular Vesicles • Brain • Maternal Health

PM PregaMind EV-OMICS Laboratory

Extracellular Vesicles and Translational Biomarkers for Brain and Maternal Health

Integrating multi-omics biology and clinical laboratory innovation to advance next-generation diagnostics.

Dr. Prasenjit Mitra

Physician–Scientist • Clinical Biochemist • Laboratory Medicine Innovator

Associate Professor — Department of Biochemistry

PGIMER Chandigarh

Founder & Principal Investigator

PM PregaMind EV-OMICS Laboratory

Extracellular VesiclesMulti-Omics BiomarkersMolecular PsychiatrySchizophrenia BiomarkersMaternal HealthGestational DiabetesTranslational DiagnosticsClinical BiochemistryLaboratory Quality SystemsAI in Laboratory MedicinePrecision DiagnosticsLaboratory InnovationExtracellular VesiclesMulti-Omics BiomarkersMolecular PsychiatrySchizophrenia BiomarkersMaternal HealthGestational DiabetesTranslational DiagnosticsClinical BiochemistryLaboratory Quality SystemsAI in Laboratory MedicinePrecision DiagnosticsLaboratory Innovation
Core Research Themes

Research Highlights

Extracellular Vesicle Biology

Studying extracellular vesicles as carriers of molecular signals linking tissues and disease processes.

Brain Disorders & Molecular Psychiatry

Identifying EV-derived biomarkers associated with schizophrenia, depression, and treatment response.

Maternal Health & Gestational Diabetes

Investigating placenta-derived extracellular vesicles to uncover biomarkers for gestational diabetes.

Translational Diagnostics

Translating molecular discoveries into clinically actionable diagnostic tools and laboratory innovations.

Our Approach

Research Philosophy

Modern medicine is entering an era where molecular biology, clinical diagnostics, and intelligent laboratory systems must converge to improve patient care. My research focuses on understanding how extracellular vesicles carry molecular signals that reflect physiological and pathological states, particularly in brain disorders and maternal health. By integrating multi-omics biology with clinical laboratory science, my goal is to translate molecular discoveries into robust diagnostic tools. At the same time, I am deeply interested in improving the way diagnostic laboratories operate—through quality systems, data-driven decision making, and emerging applications of artificial intelligence in laboratory medicine.

Scientific Identity

Research Identity at a Glance

The PM PregaMind EV-OMICS Laboratory sits at a unique convergence point — integrating extracellular vesicle biology, brain disorder research, maternal health diagnostics, and clinical laboratory innovation into a single translational science programme.

Extracellular Vesicles

EV isolation, characterisation, cargo profiling

Brain Disorders

Schizophrenia, MDD, suicidality biomarkers

Maternal Health

GDM, preeclampsia, pEV diagnostics

Clinical Diagnostics

Assay translation, precision testing

ExtracellularVesicles
BrainDisorders
MaternalHealth
ClinicalDiagnostics
PM PregaMindEV-OMICSLaboratory
Research Ecosystem

Translational Laboratory Medicine Ecosystem

Connecting extracellular vesicle biology, biomarker discovery, and intelligent diagnostic laboratories.

Research
Diagnostics
Lab Innovation
TranslationalLaboratoryMedicineExtracellularVesiclesMulti-OmicsBiologyPsychiatricBiomarkersMaternal HealthBiomarkersClinicalBiochemistryBiomarkerTranslationPrecisionDiagnosticsClinical LabPlatformsAI in LabMedicineQualitySystemsSigmaMetricsLaboratoryOperations

Hover nodes to explore

Research Cluster

  • Extracellular Vesicles
  • Multi-Omics Biology
  • Psychiatric Biomarkers
  • Maternal Health Biomarkers

Diagnostics Cluster

  • Clinical Biochemistry
  • Biomarker Translation
  • Precision Diagnostics
  • Clinical Lab Platforms

Lab Innovation Cluster

  • AI in Laboratory Medicine
  • Quality Systems
  • Sigma Metrics
  • Laboratory Operations
Active Investigations

Research Programs

Funded investigations advancing extracellular vesicle biology into translatable clinical diagnostic tools for brain and maternal health.

ICMR-Funded · 2025

Placenta-Derived Extracellular Vesicles in Gestational Diabetes

Identification of biomarkers of Gestational Diabetes Mellitus (GDM) from placenta-derived extracellular vesicles (pEVs) using an integrated proteomics and metabolomics approach. This project aims to develop non-invasive diagnostic tools for early GDM detection.

Placental EV IsolationProteomicsMetabolomicsGDM Biomarkers

ICMR Project Grant — 2025

Active Research · Ongoing

Brain-Derived Extracellular Vesicles in Schizophrenia

Characterisation of neuron-derived exosomes and microvesicles carrying schizophrenia-associated molecular cargo. This study identifies liquid biopsy biomarkers to improve early diagnosis and stratification of patients with schizophrenia.

Neuron-Derived EVsSchizophrenia BiomarkersLiquid BiopsymiRNA Profiling

AIIMS Jodhpur — Institutional Research Grant

ICMR-Funded · Active

Exosomal microRNA Biomarkers in Depression and Suicidality

Profiling of exosome-encapsulated microRNAs in patients with major depressive disorder and suicidal ideation. This research seeks to identify robust molecular signatures enabling precision psychiatry and risk stratification.

Exosomal miRNAMajor DepressionSuicide RiskPrecision Psychiatry

ICMR Project Grant — Active

Innovation

Clinical Laboratory Innovation

Transforming diagnostic laboratories through quality systems, digital infrastructure, and artificial intelligence.

View lab innovation

Laboratory Quality Systems

ISO 15189-aligned total quality management frameworks with real-time Westgard rule monitoring, Six Sigma performance evaluation, and evidence-based QC design.

ISO 15189Sigma MetricsWestgard Rules

AI in Laboratory Medicine

Machine learning models for predictive quality control, anomaly detection, AI-assisted diagnostic reporting, and intelligent test utilization management.

Machine LearningPredictive QCDecision Support

Laboratory Operations & Supply Chain

Integrated operational frameworks for inventory management, turnaround time optimisation, workflow automation, and AI-driven supply chain management.

Inventory AITAT OptimisationWorkflow Automation

Diagnostic Biomarker Translation

Converting research-grade molecular findings into validated, clinically deployable diagnostic assays — from method development to reference interval verification and regulatory compliance.

Assay ValidationReference IntervalsClinical Translation
Global Scientific Engagement

Global Scientific Engagement

Dr. Prasenjit Mitra contributes to international scientific dialogue through invited lectures, conference presentations, and professional workshops across multiple countries.

36Cities
12Countries
39+Invited Talks
Invited Talks & Leadership
Oral & Poster Presentations
Workshops & Conferences
HyderabadKuala LumpurJodhpurSydneySeoulBangaloreRomeNew DelhiGangtokJaipur

Click any marker to view all events at that location. Scroll to zoom, drag to pan.

Scholarly WorkORCID Verified

Featured Research

A selection of key scientific contributions from Dr. Prasenjit Mitra, representing landmark findings across extracellular vesicle biology, psychiatric biomarkers, environmental toxicology, and translational clinical chemistry.

All Publications
2026Research Article

AI, Automation and the Future Role of the Clinical Biochemist: from Analyzer Custodian to Clinical Knowledge Partner

Indian Journal of Clinical Biochemistry

Laboratory Medicine and Clinical Chemistry
2022Research Article

T helper cells in depression: central role of Th17 cells

Critical Reviews in Clinical Laboratory Sciences

Molecular Psychiatry
2021Research Article

Role of Genetic Variants and Gene Expression in the Susceptibility and Severity of COVID-19

Annals of Laboratory Medicine

Laboratory Medicine and Clinical Chemistry
2021Research Article

Association of microRNA expression with changes in immune markers in workers with cadmium exposure

Chemosphere

Environmental Toxicology
2020Research Article

Association of circulating BDNF levels with BDNF rs6265 polymorphism in schizophrenia

Behavioural Brain Research

Molecular Psychiatry

Publications sourced exclusively from ORCID record 0000-0003-4826-1587. No AI-generated entries.

Explore full publication list
Research Impact

Impact at a Glance

The PM PregaMind EV-OMICS Laboratory integrates extracellular vesicle biology, multi-omics biomarker discovery, and translational laboratory medicine. The laboratory contributes to international research through publications, funded projects, and global scientific engagement.

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Publications

Peer-reviewed articles

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Citations

Google Scholar

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h-index

Research influence

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Funded Projects

Active ICMR grants

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Invited Talks

Symposia & lectures

Live

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Scientific Meetings

Conferences attended

Live

20+

Countries reached

International presentations

IFCC · APFCB · PGIMER · AIIMS

Active collaborations

Global partnerships

20+

Research mentees

PhD · MD · MSc students

Blog & Commentary

Latest Insights

All insights
AI in Medicine

AI, Automation and the Future Role of the Clinical Biochemist

The question is no longer whether AI will replace the clinical biochemist—it is how AI will transform the profession's identity and competencies.

January 2026 8 min read
Read paper
Digital Health

Blockchain in Clinical Chemistry: from Hype to Clinical and Operational Value

Blockchain's immutability, decentralization, and transparency directly address longstanding pain points in laboratory data integrity, supply chains, and inter-institutional collaboration.

February 2026 6 min read
Read paper
Neurotoxicology

Unmasking Lead Exposure and Neurotoxicity: Epigenetics, EVs, and the Gut-Brain Connection

Emerging frontiers in lead neurotoxicity—from epigenetic changes and extracellular vesicle-mediated metal transfer to gut microbiome dysbiosis.

January 2025 9 min read
Read paper
Always Up to Date

Latest Activity

Recent publications, talks, and research updates from the PM PregaMind EV-OMICS Laboratory.

Latest Publication

AI, Automation and the Future Role of the Clinical Biochemist: from Analyzer Custodian to Clinical Knowledge Partner

Indian Journal of Clinical Biochemistry

2026

View Publication
Latest Invited Talk

1st Annual International Conference of the Indian Extracellular Vesicles Society (VESICON 2025)

Hyderabad, India

2025

View Talks
Latest Research Program

Identification of Biomarkers of Gestational Diabetes Mellitus from Placenta-Derived Extracellular Vesicles

Funded by ICMR

Ongoing
View Research
Open to Collaboration

Collaborate with the PM PregaMind EV-OMICS Laboratory

We welcome partnerships with clinicians, molecular biologists, data scientists, and laboratory professionals working to advance translational diagnostics and extracellular vesicle science.