AI, Automation and the Future Role of the Clinical Biochemist
The question is no longer whether AI will replace the clinical biochemist—it is how AI will transform the profession's identity and competencies.

PM PregaMind
EV-OMICS Laboratory
Extracellular Vesicles • Brain • Maternal Health
Integrating multi-omics biology and clinical laboratory innovation to advance next-generation diagnostics.
Dr. Prasenjit Mitra
Physician–Scientist • Clinical Biochemist • Laboratory Medicine Innovator
Associate Professor — Department of Biochemistry
PGIMER Chandigarh
Founder & Principal Investigator
PM PregaMind EV-OMICS Laboratory
Academic Profiles

PM PregaMind
EV-OMICS Laboratory
Studying extracellular vesicles as carriers of molecular signals linking tissues and disease processes.
Identifying EV-derived biomarkers associated with schizophrenia, depression, and treatment response.
Investigating placenta-derived extracellular vesicles to uncover biomarkers for gestational diabetes.
Translating molecular discoveries into clinically actionable diagnostic tools and laboratory innovations.
Modern medicine is entering an era where molecular biology, clinical diagnostics, and intelligent laboratory systems must converge to improve patient care. My research focuses on understanding how extracellular vesicles carry molecular signals that reflect physiological and pathological states, particularly in brain disorders and maternal health. By integrating multi-omics biology with clinical laboratory science, my goal is to translate molecular discoveries into robust diagnostic tools. At the same time, I am deeply interested in improving the way diagnostic laboratories operate—through quality systems, data-driven decision making, and emerging applications of artificial intelligence in laboratory medicine.
The PM PregaMind EV-OMICS Laboratory sits at a unique convergence point — integrating extracellular vesicle biology, brain disorder research, maternal health diagnostics, and clinical laboratory innovation into a single translational science programme.
EV isolation, characterisation, cargo profiling
Schizophrenia, MDD, suicidality biomarkers
GDM, preeclampsia, pEV diagnostics
Assay translation, precision testing
Connecting extracellular vesicle biology, biomarker discovery, and intelligent diagnostic laboratories.
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Research Cluster
Diagnostics Cluster
Lab Innovation Cluster
Funded investigations advancing extracellular vesicle biology into translatable clinical diagnostic tools for brain and maternal health.
Identification of biomarkers of Gestational Diabetes Mellitus (GDM) from placenta-derived extracellular vesicles (pEVs) using an integrated proteomics and metabolomics approach. This project aims to develop non-invasive diagnostic tools for early GDM detection.
ICMR Project Grant — 2025
Characterisation of neuron-derived exosomes and microvesicles carrying schizophrenia-associated molecular cargo. This study identifies liquid biopsy biomarkers to improve early diagnosis and stratification of patients with schizophrenia.
AIIMS Jodhpur — Institutional Research Grant
Profiling of exosome-encapsulated microRNAs in patients with major depressive disorder and suicidal ideation. This research seeks to identify robust molecular signatures enabling precision psychiatry and risk stratification.
ICMR Project Grant — Active
Transforming diagnostic laboratories through quality systems, digital infrastructure, and artificial intelligence.
ISO 15189-aligned total quality management frameworks with real-time Westgard rule monitoring, Six Sigma performance evaluation, and evidence-based QC design.
Machine learning models for predictive quality control, anomaly detection, AI-assisted diagnostic reporting, and intelligent test utilization management.
Integrated operational frameworks for inventory management, turnaround time optimisation, workflow automation, and AI-driven supply chain management.
Converting research-grade molecular findings into validated, clinically deployable diagnostic assays — from method development to reference interval verification and regulatory compliance.
Dr. Prasenjit Mitra contributes to international scientific dialogue through invited lectures, conference presentations, and professional workshops across multiple countries.
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A selection of key scientific contributions from Dr. Prasenjit Mitra, representing landmark findings across extracellular vesicle biology, psychiatric biomarkers, environmental toxicology, and translational clinical chemistry.
Indian Journal of Clinical Biochemistry
Critical Reviews in Clinical Laboratory Sciences
Annals of Laboratory Medicine
Chemosphere
Behavioural Brain Research
Publications sourced exclusively from ORCID record 0000-0003-4826-1587. No AI-generated entries.
Explore full publication listThe PM PregaMind EV-OMICS Laboratory integrates extracellular vesicle biology, multi-omics biomarker discovery, and translational laboratory medicine. The laboratory contributes to international research through publications, funded projects, and global scientific engagement.
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The question is no longer whether AI will replace the clinical biochemist—it is how AI will transform the profession's identity and competencies.
Blockchain's immutability, decentralization, and transparency directly address longstanding pain points in laboratory data integrity, supply chains, and inter-institutional collaboration.
Emerging frontiers in lead neurotoxicity—from epigenetic changes and extracellular vesicle-mediated metal transfer to gut microbiome dysbiosis.
Recent publications, talks, and research updates from the PM PregaMind EV-OMICS Laboratory.
Indian Journal of Clinical Biochemistry
2026
Hyderabad, India
2025
Funded by ICMR
OngoingWe welcome partnerships with clinicians, molecular biologists, data scientists, and laboratory professionals working to advance translational diagnostics and extracellular vesicle science.