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PreciMind

Signals. Systems. Science.

Evidence-based perspectives on laboratory medicine, diagnostic intelligence and translational science.

PreciMind examines how biological and analytical signals become clinical evidence, how laboratory systems shape patient care, and how research moves from discovery to meaningful application.

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Long-form articles, evidence-based perspectives and practical frameworks published through the PreciMind newsletter.

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What PreciMind explores

Laboratory Systems

Laboratory quality, analytical performance, patient safety, point-of-care testing, workforce, ISO 15189 and the systems that determine whether laboratory information can be trusted.

Diagnostic Intelligence

Artificial intelligence, clinical reasoning, evidence interpretation, biomarker performance and the responsible use of data in laboratory medicine.

Translational Science

Extracellular vesicles, OMICS, pregnancy, mental health, biomarker discovery, validation and the path from research finding to clinical application.

Published Editorials and Commentaries

Selected peer-reviewed editorials and scientific commentaries by Dr Prasenjit Mitra and collaborators.

Digital HealthEditorial · 2026

Blockchain in Clinical Chemistry: from Hype to Clinical and Operational Value

Published in Indian Journal of Clinical Biochemistry (2026) 41:149–151

Clinical laboratories function at the confluence of precision, accountability, and trust. In this editorial, Dr. Mitra and colleagues examine how blockchain—long associated with cryptocurrency—is finding genuine application in laboratory medicine. The article moves beyond hype to ask a sharper question: does blockchain deliver measurable value within routine laboratory workflows?

  • Blockchain offers verifiable data provenance for lab accreditation
  • Permissioned architectures align with patient confidentiality requirements
  • Federated learning + blockchain can enable privacy-preserving AI training
February 2026 6 min read
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AI in MedicineEditorial · 2026

AI, Automation and the Future Role of the Clinical Biochemist: from Analyzer Custodian to Clinical Knowledge Partner

Published in Indian Journal of Clinical Biochemistry (2026) 41:1–4

The question is no longer whether AI will replace the clinical biochemist—it is how AI will transform the profession's identity, competencies, and duties, especially in high-volume, resource-limited settings like India. This landmark editorial maps the current surge of automation across all testing phases and reconceptualizes what it means to be a clinical biochemist in an AI-enhanced era.

  • AI is transforming pre-analytical, analytical, and post-analytical phases
  • Clinical biochemists must develop AI literacy as a professional obligation
  • Governance structures—AI oversight committees—must be embedded in lab quality frameworks
January 2026 8 min read
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SustainabilityEditorial · 2025

Laboratory Medicine and Sustainability: A Call To Action

Published in Indian Journal of Clinical Biochemistry (2025) 40:319–321

Laboratories significantly contribute to healthcare waste and energy consumption. This editorial is a call to action—aligning laboratory medicine with the UN Sustainable Development Goals and outlining actionable strategies from green chemistry principles to carbon footprint reduction and sustainable procurement.

  • Laboratory operations contribute measurably to healthcare carbon footprints
  • Green chemistry and sustainable procurement reduce hazardous waste
  • Aligning labs with UN SDGs creates both environmental and economic benefits
June 2025 7 min read
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NeurotoxicologyEditorial · 2025

Unmasking Lead Exposure and Neurotoxicity: Epigenetics, Extracellular Vesicles, and the Gut-Brain Connection

Published in Indian Journal of Clinical Biochemistry (2025) 40:1–3

Lead (Pb) remains a hidden danger to public health. This editorial synthesizes emerging mechanistic frontiers—epigenetics, extracellular vesicles, and the gut-brain microbiota axis—revealing why no blood lead level is truly safe, and why the biological consequences of exposure extend far beyond classical toxicology.

  • No blood lead level is considered safe for human health
  • EVs can transport lead between cells, propagating neurotoxic signals
  • Epigenetic mechanisms link chronic lead exposure to Alzheimer's and Parkinson's
January 2025 9 min read
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Dr Prasenjit Mitra, clinical biochemist, researcher and medical educator

About the author

Dr Prasenjit Mitra is a clinical biochemist, researcher and medical educator working across laboratory quality, diagnostic intelligence, extracellular vesicles and translational research. PreciMind is the editorial and knowledge-sharing channel within his wider professional platform.

Evidence deserves interpretation. Science needs translation.

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